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Striatin, calmodulin binding protein 4 pseudogene

Molecular classification
Pseudogene
01

Overview

Striatin, calmodulin binding protein 4 pseudogene is a nonfunctional genomic DNA segment closely related in sequence to the functional STRN4 gene, which encodes a calmodulin-binding scaffolding protein involved in key signaling pathways. As a pseudogene, it does not encode a functional protein, lacks apparent biological function, and is not considered a drug target. Pseudogenes may sometimes influence gene regulation, but no known regulatory, disease, or pharmacological functions are associated with this particular pseudogene[5][9]. Key point: *ENSG00000277146 is not an active gene, enzyme, receptor, or transporter; it is a pseudogene and thus not appropriate as a therapeutic target. If a functional STRN4 gene or protein is intended, STRN4 (striatin 4, ENSG00000090372) should be used instead[1][4].*

Other names
STRN4 pseudogeneStriatin-4 pseudogenestriatin, calmodulin binding protein 4 processed pseudogene
02

Biological functions

Other (pseudogenes generally lack biological function as proteins; some may have regulatory RNA functions, but none are established for this specific pseudogene)
03

Disease associations

Other (no known direct disease role specific to this pseudogene; some pseudogenes can regulate parental gene expression or serve as biomarkers in other contexts, but no such role is described for this locus)

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