SUGT1P4-STRA6LP-CCDC180 readthrough (SUGT1P4-STRA6LP-CCDC180)

SUGT1P4-STRA6LP-CCDC180 readthrough is an RNA locus joining an upstream pseudogene (SUGT1P4) and a downstream protein-coding gene (CCDC180)[1][2][5]. The resulting transcripts are likely degraded by nonsense-mediated decay and are not thought to produce protein. While the CCDC180 component is associated with Behçet’s Disease based on GWAS studies, the readthrough itself is not considered a canonical molecular target, nor does it have a defined molecular function, clinical indication, drug interaction profile, or biomarker status. The target name combines several loci and is scientifically imprecise as a therapeutic or diagnostic entity[1][3][5]. Note: If structure-function or drug target information is required, the focus should be only on the protein-coding CCDC180 gene, not the readthrough transcript, which is non-functional[1][3][5]. The entry as queried is best considered incorrect or noncanonical for drug target review.

Other names

LOC100499484-C9ORF174Behcet's Disease Associated Gene 1 (BDAG1)LOC100499484-C9orf174 readthroughC9ORF174KIAA1529