Sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone-preferring, member 1 pseudogene (SULT2A1 pseudogene (no established abbreviation))

Sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone-preferring, member 1 pseudogene (ENSG00000276578) is a non-functional DNA segment that resembles the SULT2A1 gene but does not encode an active enzyme. The presence of processed pseudogenes in the human genome is common, and they typically result from retrotransposition events. These pseudogenes lack functional protein-coding capacity and are not transcribed into functional products, distinguishing them from genuine therapeutic molecular targets such as receptors, enzymes, or transporters[1][3][4][6]. They may occasionally have minor effects through genetic regulation, but no such function is reported or relevant for this gene entry. For canonical, druggable SULT2A1 information, consult the functional gene rather than the pseudogene; SULT2A1 is an active cytosolic enzyme that catalyzes the sulfation of DHEA (dehydroepiandrosterone) and other steroids, with established biological and pharmacological importance[5]. However, ENSG00000276578 is **not** the active SULT2A1, but its pseudogene—there is no protein product, function, or therapeutic relevance.

Other names

AC004696.1SULT2A1PSULT2A2P

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