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Target intelligence / Profile preview
Superoxide Dismutase (Mimetic) (SOD mimetic)
- Target
- SOD mimetic
- Molecular classification
- Enzyme Mimetic, Small Molecule
01
Overview
Superoxide dismutase (SOD) mimetics are synthetic compounds designed to replicate the activity of the native superoxide dismutase enzyme. Their primary function is to catalyze the conversion of superoxide anion (\(O_2^-\)), a reactive oxygen species, into hydrogen peroxide (\(H_2O_2\)), which is subsequently broken down into water by catalase. This process helps protect cells from oxidative stress and damage caused by reactive oxygen species, which are implicated in cancer, neurodegeneration, aging, and inflammatory diseases.
- Other names
- SODSuperoxide dismutase mimicMnSOD mimic
02
Mechanism of action
Catalyzes the dismutation of superoxide radicals into hydrogen peroxide and oxygen.
03
Biological functions
AntioxidantReactive Oxygen Species ScavengingRedox Balance Regulation
04
Disease associations
CancerNeurodegenerative diseaseInflammationAgingIschemia-Reperfusion Injury
05
Safety considerations
Purity and stability of the mimeticPotential for off-target effectsToxicity of metal center
06
Interacting drugs
Rucosopasem manganese
1 more in the full profile.
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