Suppression of tumorigenicity 13 (Hsp70 interacting protein) pseudogene 15 (ST13P15)

Suppression of tumorigenicity 13 (Hsp70 interacting protein) pseudogene 15 (ST13P15) is annotated as a human pseudogene corresponding to the functional **ST13** gene, which encodes the Hsp70 interacting protein (Hip), a co-chaperone of heat shock protein 70 (Hsp70)[1][4]. Pseudogenes, including ST13P15, do not produce a functional protein and typically arise from gene duplication or retrotransposition events that then accumulate mutations rendering them non-functional[2]. There is no evidence that ST13P15 itself acts as a therapeutic target, nor is it involved in any known molecular pathways, biological functions, or disease roles; these features distinguish it from the functional ST13 gene, which does play a role in protein homeostasis and possibly tumor suppression but is not directly implicated for ST13P15[2][5]. No drugs, mechanisms of action, or biomarkers are associated with ST13P15, and there are no reported safety concerns[1][2]. **Note:** While the parent gene ST13 has described biological roles (as a co-factor for Hsp70), **ST13P15 is a pseudogene and does not share these properties**. Thus, requests for it as a therapeutic target are considered incorrect or not meaningful in the context of drug discovery or clinical application[2][5].

Other names

ST13P15suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudogene 15

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