Suppression of tumorigenicity 13 pseudogene (ST13P)

Suppression of tumorigenicity 13 pseudogene (Ensembl: ENSG00000258230) is a non-protein-coding segment of human DNA that closely resembles the functional ST13 gene but does not encode a protein product[4][6][16]. The parent gene, ST13, encodes a co-chaperone protein (Hsc70-interacting protein, HIP) that modulates heat shock protein activity and has been proposed, though not conclusively proven, as a tumor suppressor[1][7]. However, the pseudogene variant referenced here does not contribute directly to cellular biological functions or disease processes and is not a therapeutic target. There is no documented role for this specific pseudogene as a biomarker, drug target, or in disease pathology, and it is primarily of interest as a genomic annotation[4][6][16]. Note: If you are interested in the functional protein-coding gene *Suppression of tumorigenicity 13* (ST13/HIP), this is a different entity with potential—though as yet only limited—association with tumor suppression[1][7][13]. The pseudogene does not share those properties.

Other names

Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudogeneST13PGC12M102166GC12M101774GC12M101809GC12M101899GC12M102002GC12M102110GC12M102253GC12M102378GC12M102488GC12M102600GC12M102716GC12M102842GC12M102968GC12M103078