Suppressor of cytokine signaling 2 pseudogene (null)

Suppressor of cytokine signaling 2 pseudogene (ENSG00000236867), sometimes referred to as SOCS2P1, is a human pseudogene related to the functional suppressor of cytokine signaling 2 (SOCS2) gene[2]. Unlike the protein-coding SOCS2 gene—which encodes a cytosolic protein involved in negative regulation of cytokine receptor signaling via the JAK/STAT pathway and plays roles in immune and growth factor signaling[1]—the pseudogene variant does not encode a protein and has no demonstrated biological or therapeutic role. There are multiple SOCS2 pseudogenes mapped to the human genome[1], and while annotation resources list them by name and sequence, there is no evidence of their direct involvement in protein expression, physiological pathways, or disease. Key clarification: If a therapeutic target or receptor is sought, reference should be made to the functional "Suppressor of cytokine signaling 2" (SOCS2, ENSG00000120833) rather than this pseudogene[1][2]. The pseudogene is a non-coding genomic element and not a target for pharmacological modulation.

Other names

SOCS2P1suppressor of cytokine signaling 2 pseudogene 1

null