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Suppressor of zeste 12 homolog pseudogene 1 (SUZ12P1)
- Target
- SUZ12P1
- Molecular classification
- Other (Pseudogene)
01
Overview
Suppressor of zeste 12 homolog pseudogene 1 (SUZ12P1, ENSG00000270618) is a non-coding pseudogene in humans, resembling the functional gene SUZ12. While SUZ12 is an essential component of the polycomb repressive complex 2 (PRC2) that regulates gene expression through histone methylation, SUZ12P1 does not produce a functional protein and is not considered a molecule with therapeutic relevance. Pseudogenes typically lack direct biological function or disease association, though rare exceptions involve regulatory noncoding RNA activities. Confusion sometimes arises due to similarity with SUZ12, which is implicated in epigenetic regulation and certain cancers.
- Other names
- SUZ12 pseudogene 1suppressor of zeste 12 homolog pseudogene 1SUZ12P1
02
Biological functions
Other (No confirmed direct biological function; non-coding. Functional SUZ12 is involved in chromatin regulation, but the pseudogene may have regulatory roles through RNA, if any.)
03
Disease associations
Other (The functional SUZ12 gene is implicated in cancer, but the pseudogene is not a validated disease gene. Some pseudogenes may have roles in cancer biology by acting as long noncoding RNAs, but SUZ12P1 is not directly identified in this context.)
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