Target intelligence / Profile preview

Surfeit locus protein 6 (SURF6)

Target: SURF6
Molecular classification: Nuclear protein, Nucleolar matrix protein, RNA-binding protein, DNA-binding protein

Overview

Surfeit locus protein 6 (SURF6) is a highly conserved nucleolar matrix protein encoded by the SURF6 gene. This protein exhibits high binding capacity for both RNA and DNA but binds more strongly to RNA. It is predominantly located in the nucleolar granular component, implicated in ribosome assembly and maturation, and is expressed ubiquitously, consistent with a housekeeping gene. There are several transcript variants due to alternative splicing. SURF6 does not belong to any major receptor or enzyme families and is not considered a drug target at present.

Other names: Surfeit 6surf6Surfeit locus protein 6

Mechanism of action

Not applicable as there are no drugs or therapeutic interventions targeting SURF6

Biological functions

Ribosome biogenesisNucleic acid binding (DNA and RNA)Possible involvement in ribosomal biosynthesis or assembly

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