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Sushi domain-containing protein 1 (SUSD1)
- Target
- SUSD1
- Molecular classification
- Other (Sushi domain-containing protein; not classified as receptor, enzyme, transporter, or classic signaling protein)
01
Overview
Sushi domain-containing protein 1 (SUSD1) is a human protein encoded by the SUSD1 gene, located on chromosome 9. SUSD1 contains evolutionarily conserved Sushi domains, also known as complement control protein (CCP) modules or short consensus repeats (SCR), which are commonly found in proteins related to complement regulation and cell adhesion but not typically associated with direct druggability or therapeutic targeting. SUSD1 is predicted to enable calcium ion binding and is membrane-associated, but there is limited functional characterization. Its primary associations are with rare genetic disorders such as Seckel syndrome, but no evidence currently supports its designation as a therapeutic target, biomarker, or known point of drug interaction.
- Other names
- Sushi domain-containing protein 1SUSD1UNQ2438/PRO4999DKFZP761E1824
02
Biological functions
Calcium ion binding (predicted)Membrane localization (predicted)
03
Disease associations
Seckel syndrome 1 (associative, not necessarily causal)Seckel syndrome
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