Synaptonemal complex protein 3 pseudogene

Synaptonemal complex protein 3 pseudogene (ENSG00000270728) is a genomic sequence related to the protein-coding gene SYCP3 but does not encode a functional protein[1][2][5]. Pseudogenes like this arise through duplication or retrotransposition processes and typically lack functional protein-coding capacity; they may contain mutations, deletions, or lack essential regulatory elements needed for protein production[2][5]. Although pseudogenes can sometimes modulate gene expression by acting as microRNA decoys, no specific regulatory or functional role has been described for ENSG00000270728[5]. This pseudogene is sometimes confused with the protein-coding SYCP3 gene, which is an essential structural component of the synaptonemal complex involved in meiosis and fertility[4][7]. However, ENSG00000270728 itself is not a classical drug target, does not interact with drugs, and is not implicated in disease or used in diagnostics. If you are seeking information on the functional counterpart, refer to synaptonemal complex protein 3 (SYCP3, ENSG00000139351), which is a meiosis-specific structural protein[6][7]. The pseudogene described here is not suitable for therapeutic targeting and does not fit traditional target classifications.

Other names

Synaptonemal complex protein 3 pseudogeneSYCP3P