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Synovial sarcoma translocation gene on chromosome 18-like 1 pseudogene (ENSG00000271559)
- Target
- ENSG00000271559
- Molecular classification
- Other (Pseudogene)
01
Overview
The "synovial sarcoma translocation gene on chromosome 18-like 1 pseudogene" (ENSG00000271559) is a non-functional genomic sequence with homology to the synovial sarcoma translocation gene (SS18/SYT) but does not encode a functional protein product. Pseudogenes such as this are generally classified as genetic relics and, unless specifically shown otherwise, do not have direct biological or pathological roles. The canonical SS18 protein is implicated in synovial sarcoma due to somatic chromosomal translocations producing fusion proteins with SSX1 or SSX2[7][4], but the pseudogene variant itself is not involved in disease mechanisms and is not therapeutically actionable[2][5][8].
- Other names
- SS18 pseudogeneSYT pseudogeneSynovial sarcoma translocation gene pseudogeneChromosome 18-like 1 pseudogene
02
Biological functions
Other (pseudogenes usually lack direct biological functions due to their inability to produce functional protein, though some pseudogenes may have regulatory roles at the RNA level—there is no evidence for functionality for this specific pseudogene as per search results)
03
Disease associations
Other (No confirmed disease role; parent gene SS18 is involved in cancer, specifically synovial sarcoma, but the pseudogene itself is not)
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