Target intelligence / Profile preview

Plasma Iron Transport (N/A)

Target
N/A
Molecular classification
Transport System, Protein-Protein Interaction, Hormonal Regulation
01

Overview

Plasma iron transport refers to the physiological process by which iron is carried through the bloodstream, primarily bound to specific proteins, and delivered to cells throughout the body. This system is essential for maintaining iron homeostasis, supporting cellular functions such as oxygen transport (via hemoglobin), DNA synthesis, and energy metabolism. Key molecules involved include transferrin, transferrin receptors, ferroportin, and hepcidin. Dysregulation can lead to iron deficiency or overload disorders.

Other names
Systemic iron homeostasisIron metabolismIron trafficking
02

Mechanism of action

Varies depending on the specific drug; includes increasing iron absorption, binding and removing excess iron, or modulating hepcidin activity.

03

Biological functions

Iron transportOxygen transportErythropoiesisIron storageRegulation of iron levels
04

Disease associations

Iron deficiency anemiaHemochromatosisAnemia of chronic diseaseInflammation
05

Safety considerations

Iron overloadIron deficiencyDrug interactionsToxicity from free iron
06

Interacting drugs

Iron supplements

2 more in the full profile.

07

Biomarkers

Serum ironTransferrin saturationFerritinHepcidin levelsTransferrin receptor levels

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