Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
T-cell immunoglobulin and mucin domain-containing protein 1 (TIM-1)
- Target
- TIM-1
- Molecular classification
- Type I transmembrane glycoprotein, Receptor
01
Overview
TIM-1 is a type I transmembrane glycoprotein involved in T-cell activation, immune regulation, and tissue regeneration. It is overexpressed in various cancers and implicated in autoimmunity. It acts as a stimulatory molecule for T-cell activation, promoting proliferation and cytokine secretion by T cells and can mediate both co-stimulatory and co-inhibitory signals depending on context.
- Other names
- HAVCR1KIM-1
02
Mechanism of action
Targeted silencing inhibits cancer cell growth/progression.
03
Biological functions
T-cell activationCell proliferationCytokine secretionImmune responseClearance of dying cells
04
Disease associations
CancerAutoimmunityCardiovascular diseaseKidney injury
05
Safety considerations
Potential for autoimmune complications with TIM-1 blockade.
06
Biomarkers
KIM-1 (Kidney injury marker)
Beyond the preview
Go deeper on T-cell immunoglobulin and mucin domain-containing protein 1 (TIM-1).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on T-cell immunoglobulin and mucin domain-containing protein 1 (TIM-1).