T cell receptor alpha joining 7 (TRAJ7)

TRAJ7 (T cell receptor alpha joining 7) is a gene segment within the T cell receptor alpha locus, encoding one of many possible joining regions recombined during T cell development. VJ recombination in the alpha locus uses TRAJ segments like TRAJ7 to generate the antigen-binding diversity found in T cell receptors. TRAJ7 does not encode a protein by itself; instead, it contributes as a module to the assembled variable region of the receptor as part of somatic DNA rearrangement[1][3][4]. TRAJ7 is not a pharmacological target, but it is essential for immune diversity and function as part of the broader TCR complex[2][5]. If you require information on the complete *T cell receptor alpha chain* or the *T cell receptor complex*—which are canonical therapeutic targets—please clarify, as TRAJ7 alone is a joining segment and not a conventional drug target[1][2].

Other names

TRAJ7Gm16919NCBI Gene: 28748Ensembl: ENSG00000211882