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Target intelligence / Profile preview
T-cell receptor beta chain variable region 10 (TRBV10)
- Target
- TRBV10
- Molecular classification
- Receptor, Protein domain, Gene segment
01
Overview
The T-cell receptor (TCR) beta chain variable region 10 (TRBV10) is a specific member of the variable region gene segments that encode the beta chain of the TCR, a critical component in adaptive immunity. The TCR is found on the surface of T lymphocytes and is responsible for recognizing antigenic peptides presented by major histocompatibility complex (MHC) molecules on antigen-presenting cells. Diversity in this region allows recognition of a vast array of antigens.
- Other names
- Vβ10
02
Biological functions
Antigen recognitionAdaptive immune responsePeptide-MHC binding
03
Disease associations
Autoimmune diseasesLymphoproliferative disordersInfectionCancer
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