Target intelligence / Profile preview

T cell receptor Vβ10 (Vβ10)

Target
Vβ10
Molecular classification
Receptor, T cell receptor subunit
01

Overview

T cell receptor (TCR) Vβ10 refers to a specific variable region (Vβ10) of the β chain in the TCR complex, which is expressed on the surface of certain subsets of T cells. The Vβ10 segment contributes to antigen specificity by participating in the recognition of peptide-MHC complexes.

Other names
TRBV10
02

Mechanism of action

T cell activation via peptide-MHC binding

03

Biological functions

Antigen recognitionT cell activationImmune response
04

Disease associations

Autoimmune diseaseInfectionCancer
05

Safety considerations

Off-target effectsCytokine release syndromeAutoimmunity
06

Biomarkers

T cell subset markerClonal expansion marker

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