Target intelligence / Profile preview

T-cell surface glycoprotein CD1a (CD1a)

Target
CD1a
Molecular classification
Antigen-presenting molecule, Transmembrane glycoprotein, MHC class I-like molecule
01

Overview

CD1a is a transmembrane glycoprotein that presents lipid and glycolipid antigens to T-cell receptors, playing a crucial role in the immune response. It is structurally related to the major histocompatibility complex (MHC) proteins and forms heterodimers with beta-2-microglobulin. CD1a is primarily involved in presenting antigens to natural killer T-cells, which are important for recognizing and responding to lipid-based antigens from pathogens or self-antigens[2][3][5].

Other names
CD1a moleculeCluster of Differentiation 1a
02

Mechanism of action

Presentation of lipid and glycolipid antigens to T-cell receptors, facilitating immune responses.

03

Biological functions

Immune responseAntigen presentationLipid and glycolipid antigen presentation
04

Disease associations

InfectionAutoimmune diseasesCancer
05

Safety considerations

Potential for immune system modulation, which could lead to adverse effects if not properly managed.

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