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CD1a is a transmembrane glycoprotein that presents lipid and glycolipid antigens to T-cell receptors, playing a crucial role in the immune response. It is structurally related to the major histocompatibility complex (MHC) proteins and forms heterodimers with beta-2-microglobulin. CD1a is primarily involved in presenting antigens to natural killer T-cells, which are important for recognizing and responding to lipid-based antigens from pathogens or self-antigens[2][3][5].
Presentation of lipid and glycolipid antigens to T-cell receptors, facilitating immune responses.
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