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Target intelligence / Profile preview
T Cell Surface Protein (None)
- Target
- None
- Molecular classification
- Receptor, Co-receptor, Adhesion Molecule, Chemokine Receptor, Enzyme, Glycoprotein
01
Overview
T cell surface proteins are a diverse group of molecules expressed on the plasma membrane of T lymphocytes. These proteins play essential roles in antigen recognition, cell signaling, adhesion, migration, and immune regulation. They are crucial for T cell development, activation, and effector functions. Different subsets of T cells are defined by unique combinations of surface markers, such as CD4 and CD8, which dictate their function and target specificity.
- Other names
- T lymphocyte surface antigenT cell markerT cell receptorCD markers
02
Mechanism of action
Varied, depending on the specific protein. Examples include: receptor blockade, signal modulation, immune checkpoint inhibition, T cell depletion.
03
Biological functions
Antigen recognitionSignal transductionCell adhesionCell migrationImmune regulationT cell activationCo-stimulation
04
Disease associations
Autoimmune diseasesInfectious diseasesCancerImmunodeficiency
05
Safety considerations
ImmunosuppressionCytokine release syndromeAutoimmunityOpportunistic infections
06
Interacting drugs
Monoclonal antibodies (e.g., anti-CD3, anti-CD4, anti-CD8)
3 more in the full profile.
07
Biomarkers
CD4/CD8 ratio (HIV)PD-L1 expression (cancer)Specific T cell subsets in autoimmune diseases
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