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T lymphocyte subset replacement refers to the process or phenomenon by which different subsets of T lymphocytes (T cells) are replaced, reconstituted, or shifted within the immune system. This can occur naturally, as a result of disease, or through therapeutic interventions. It encompasses alterations in the balance between naive, effector, central memory, effector memory, tissue-resident memory, stem-like memory, and regulatory T cell populations, influencing overall immune competence and disease outcomes.
Varies depending on the specific intervention. Can involve selective depletion of subsets, expansion of desired subsets, or modulation of differentiation pathways.
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