Target intelligence / Profile preview

TAB3 antisense RNA 1 (TAB3-AS1)

Target
TAB3-AS1
Molecular classification
Long non-coding RNA, Antisense RNA, Natural antisense transcript
01

Overview

**TAB3 antisense RNA 1 (TAB3-AS1)** is a natural long non-coding RNA produced from the antisense strand of the genomic locus near the TAB3 gene. Like other antisense RNAs, it is believed to play a regulatory role in gene expression, often by forming complementary base pairs with mRNA transcripts from the sense strand, potentially modulating their stability, splicing, translation, or degradation[3][7][1][6]. Antisense RNAs are recognized as important components of post-transcriptional gene regulation in many organisms, but there is no specific evidence that TAB3-AS1 itself is a direct therapeutic target, disease biomarker, or associated with drug interaction in the current literature and scientific databases[3][7][1][6].\n\n**Additional Context:**\n- **General antisense RNA biology:** Antisense RNAs, particularly long non-coding types, often act locally (in cis) or at distant loci (in trans) to regulate genes at the transcriptional, post-transcriptional, or epigenetic level. They have been increasingly studied for their roles in cell differentiation, response to stress, and pathologies such as cancer, but the majority—including TAB3-AS1—have yet to be specifically validated as direct therapeutic targets or clinical biomarkers[2][4][6].\n- **Aliases:** The abbreviation CXorf29 is a previous gene symbol for the same locus[7].\n\n**Note:** There is no evidence of direct drug interactions, validated roles in specific diseases, or utility as a biomarker or target for TAB3-AS1 as of the current search. It is classified as a lncRNA/antisense RNA locus[3][7].

Other names
CXorf29OTTHUMG00000021331
02

Biological functions

Gene expression regulationEpigenetic regulationModulation of mRNA stability and/or translation

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