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TAB3 antisense RNA 2 (TAB3-AS2) is annotated as a predicted long non-coding RNA transcribed in the antisense orientation to the TAB3 gene[3]. Antisense RNAs, in general, can regulate their sense genes via transcriptional interference, RNA duplex formation, splicing modulation, or epigenetic chromatin alteration[2][5]. The functional characterization and biological role of TAB3-AS2 itself are unknown, and there are no reports describing its molecular activity, disease relevance, or druggability; as such, it should not be considered a validated therapeutic target. The entry appears incomplete and may represent a computationally predicted transcript with limited or no experimental validation. Further research is required to determine its function, expression patterns, and potential significance in physiology or disease.
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