TAF4b RNA polymerase II, TATA box binding protein-associated factor, 105kDa pseudogene

This entry represents a pseudogene related to the TAF4B gene, which encodes a component of the general transcription factor TFIID essential for RNA polymerase II-mediated transcription. However, ENSG00000234841 itself does not encode a functional protein or act as a therapeutic target. The term "pseudogene" here indicates it may share sequence similarity with TAF4B but is not transcribed or translated into a functional protein[1]. Functional TAF4B (not this pseudogene) acts as a transcriptional coactivator, mediates activation of certain antiapoptotic genes, and is implicated in human fertility and B-cell gene regulation[3][7]. Pseudogenes such as ENSG00000234841 are not considered viable therapeutic targets and do not have known roles in disease or known pharmacological interactions[1]. If you require information about the functional TAF4B gene (which is a bona fide transcription factor and has a role in cell transcription and some reproductive disorders), data should be referenced for ENSG00000141384 or the gene symbol TAF4B[3][4][7].

Other names

LOC100422627TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa pseudogene