TAT antisense RNA 1 (TAT-AS1)

TAT antisense RNA 1 (TAT-AS1) is annotated in the HGNC database as a gene encoding a natural antisense RNA. There is no evidence in the literature or major sequence databases that TAT-AS1 functions as a therapeutic target, receptor, enzyme, transporter, or transcription factor. No functional studies, disease associations, known biological processes, or drug interactions have been described for TAT-AS1, and it does not appear in common target compendia. The presence of TAT-AS1 in variant databases (e.g., ClinVar) is as a noncoding RNA locus whose function is unknown, not as a pathogenic mediator. There is a similarly named HIV-1 Tat protein (often targeted for HIV research), but TAT-AS1 is distinct and unrelated to the HIV Tat protein. Most references to antisense RNAs (including examples such as TALAM1 and antisense lncRNAs at other loci) discuss their general regulatory roles but do not relate specifically to TAT-AS1. No evidence supports TAT-AS1 being misspelled, but it is not an established drug target. The "is_incorrect" flag is set true because its inclusion as a target is misleading. No information is available regarding interacting drugs, mechanism of action, biomarker utility, disease involvement, or safety concerns for TAT-AS1. TAT antisense RNA 1 (TAT-AS1) is a long noncoding antisense RNA gene, not currently considered a therapeutic target or functionally characterized molecule. There is no structured information available on its biology, classification, disease associations, or drug relevance.

Other names

TAT-AS1