TBC domain family member 3 pseudogene 3 (TBC1D3P3)

TBC1 domain family member 3 pseudogene 3 (TBC1D3P3, ENSG00000278160) is a human pseudogene classified by HGNC as non-protein-coding[3]. Pseudogenes are genomic DNA sequences similar to functional genes but typically lack protein-coding potential due to mutations or lack of expression[3]. TBC1D3P3 shows sequence similarity to the TBC1D3 gene family, which in functional members is involved in GTPase signaling and vesicle trafficking[2]. However, as a pseudogene, TBC1D3P3 is not believed to encode a functional protein or possess recognized biological functions, disease roles, or clinical relevance as a therapeutic target[3][1]. The Ensembl gene ID ENSG00000278160 matches TBC1D3P3, confirmed as a pseudogene by academic and commercial databases[3][1]. Pseudogenes like TBC1D3P3 may impact genomic regulation or expression patterns, but do not act as receptors, enzymes, or direct therapeutic targets[1][3]. No evidence links TBC1D3P3 to disease, drug interaction, or molecular function as with other TBC1D3 gene family members[3][1]. By convention, pseudogene entries are not considered therapeutic targets and have limited direct biomedical application. TBC1D3P3 is a pseudogene, not a protein or receptor, and thus not a drug target[3][1]. There is no evidence of disease or drug associations. The entry is accurate in nomenclature, but as a pseudogene, it does not meet the criteria for a therapeutic target. If you intended a protein-coding gene from the TBC1D3 family (such as TBC1D3B), those have function as GTPase-activating proteins for RAB GTPases and potential disease associations[2], but the specific queried pseudogene (ENSG00000278160, TBC1D3P3) lacks such attributes[3][1].

Other names

TBC1D3P3TBC1 domain family member 3 pseudogene 3