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TBC1 domain family member 13 (TBC1D13)

Target: TBC1D13
Molecular classification: Enzyme, GTPase-activating protein

Overview

TBC1 domain family member 13 (TBC1D13) is a protein in humans encoded by the TBC1D13 gene. It is a GTPase-activating protein (GAP) for RAB35, and is thought to function in the regulation of insulin-induced glucose transporter (GLUT4/SLC2A4) trafficking, an essential process in cellular glucose uptake. TBC1D13 may play a broader role in intracellular protein transport, particularly in tissues responsive to insulin, although its physiological and disease-related functions require further elucidation[2][3][4][6].

Other names: TBC1D13

Biological functions

GTPase activation (specifically for RAB35)Regulation of insulin-induced glucose transporter trafficking (GLUT4/SLC2A4)Intracellular protein transport

Disease associations

Other (no direct disease roles currently established; possible involvement in metabolic regulation)

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