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Target intelligence / Profile preview
TBC1 domain family member 19 (TBC1D19)
- Target
- TBC1D19
- Molecular classification
- Enzyme, GTPase-activating protein for Rab family proteins, Other (Rab GTPase-activating protein)
01
Overview
TBC1 domain family member 19 (TBC1D19) is a protein-coding gene encoding a putative GTPase-activating protein likely acting on the Rab family of small GTPases. These proteins generally regulate vesicular trafficking in cells. TBC1D19's exact biological roles are still largely unclear; it may participate in the regulation of catalytic activities, with a presumptive role as a GTPase-activating protein (GAP), yet direct functional studies are limited. No clear links to disease, drug interactions, or clinical utility as a biomarker or therapeutic target are reported in current resources. The protein's UniProt accession is Q8N5T2. In summary, TBC1 domain family member 19 (TBC1D19) is a poorly characterized enzyme (GTPase-activating protein), not currently used as a drug target or biomarker, with no major clinical relevance established as of now.
- Other names
- TBC1 domain family member 19TBC1D19FLJ11082
02
Mechanism of action
None described (as no drugs currently target TBC1D19 directly)
03
Biological functions
GTPase activator activity (predicted/enabled)Regulation of catalytic activity
04
Disease associations
No prominent or specific disease associations with "TBC1D19" are reported in current databases.One mention considers possible roles in tumorigenesis for fusion proteins involving TBC1D19 (e.g., RBL2-TBC1D19 fusion), but this is not a well-characterized general disease function and appears rare.
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