TBC1 domain family member 3 pseudogene 1 (TBC1D3P1)

TBC1 domain family member 3 pseudogene 1 (TBC1D3P1) is a non-protein-coding genomic element classified as a pseudogene related to the TBC1D3 subfamily. TBC1D3 genes encode RabGAP domain-containing proteins, which participate in the regulation of intracellular membrane trafficking and vesicle dynamics in cells[1][5]. However, TBC1D3P1, as a pseudogene, is generally predicted not to produce a functional protein and thus does not exhibit direct biological activity, molecular function, or established involvement in human disease or pharmacology. The naming and annotation of this locus may vary, but current understanding denotes it as non-functional[5]. TBC1D3 functional family members, not pseudogenes, modulate signaling pathways (e.g., growth factor signaling, endocytic vesicle release, micropinocytosis) and can influence extracellular vesicle (EV) payload and cell signaling responses[1]. Pseudogenes like TBC1D3P1 sometimes have regulatory RNA functions, but there is no direct evidence for such a role for TBC1D3P1 at this time. Confusion may arise from the presence of both functional paralogs (e.g., TBC1D3, TBC1D3F) and multiple pseudogenes within this gene family[5]. There are no known drugs, biomarkers, or safety concerns relevant to TBC1D3P1, and it is not a recognized therapeutic or diagnostic target. If your intention was to reference a functional protein from the TBC1D3 family (such as TBC1 domain family member 3, TBC1D3), you should use the functional gene/protein name rather than the pseudogene form.

Other names

TBC1D3P1