Target intelligence / Profile preview

TBC1 domain family member 3 pseudogene 2 (TBC1D3P2)

Target
TBC1D3P2
Molecular classification
Other (pseudogene)
01

Overview

TBC1 domain family member 3 pseudogene 2 (TBC1D3P2) is a non-coding human pseudogene related to the TBC1D3 gene family, which is characterized by hominoid-specific expansions in the human genome[1]. Pseudogenes such as TBC1D3P2 are typically non-functional remnants of protein-coding genes and are not considered therapeutic targets. While gene family members like TBC1D3 are implicated in neurodevelopment, proliferation, and various signaling pathways[1][2][3], TBC1D3P2 itself does not encode a functional protein. There is limited data about its function or biomedical relevance, although one genome-wide RNAi phenotype links it to an increased infection phenotype in the context of vaccinia virus in human cells[5].

Other names
TBC1D3P2
02

Biological functions

Based on limited genome-wide RNA interference data, TBC1D3P2 may be associated with "increased vaccinia virus infection" phenotypeNo well-established biological function, as pseudogenes are typically non-functional or only function as regulatory elements.
03

Disease associations

Other (no established disease association; pseudogene does not have known direct roles in human diseases)

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