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TBL1XR1 antisense RNA 1 (TBL1XR1-AS1) is a long noncoding RNA transcribed from the opposite strand of the TBL1XR1 locus on human chromosome 3. It is distinct from the protein-coding gene TBL1XR1, which encodes a transcriptional corepressor/coactivator implicated in cell cycle, apoptosis, and tumorigenesis[1][2][3][4][5]. There is very limited information about TBL1XR1-AS1’s function, clinical relevance, or druggability in the literature. Most research and therapeutic interest is focused on the protein TBL1XR1, not its antisense RNA transcript.
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