TEN1-CDK3 readthrough (non-protein coding) (TEN1-CDK3)

The TEN1-CDK3 readthrough locus is a naturally occurring transcript that spans the adjacent TEN1 and CDK3 genes on chromosome 17[1][3][7]. This transcript is classified as a candidate for nonsense-mediated mRNA decay and is generally not translated into a protein product. TEN1 by itself is a protein involved in the CST complex, which is essential for telomere end protection and length regulation, acting in concert with proteins such as STN1 and Cdc13[2][4][6]. However, the TEN1-CDK3 readthrough does not encode a functional protein and is not characterized as a molecular target for therapeutic intervention. If you require structured data about individual protein-coding genes (TEN1 or CDK3), each has well-documented functions: TEN1 is critical for telomere maintenance, whereas CDK3 is a cyclin-dependent kinase involved in cell cycle regulation[4][5][6]. This specific readthrough transcript is mostly considered a transcriptional byproduct with no established direct roles in molecular targeting or disease.

Other names

TEN1C17orf106C17orf106-CDK3TEN1-CDK3CST complex subunit TEN1Protein telomeric pathway with STN1 homologTelomere length regulation protein TEN1 homolog