Target intelligence / Profile preview

Testis-expressed protein 13B (TEX13B)

Target
TEX13B
Molecular classification
Other
01

Overview

Testis-expressed protein 13B (TEX13B) is a protein-coding gene mainly expressed in the testis, specifically in male germ cells such as spermatogenic cells and mature sperm nuclei[1][2][3][5]. In the mouse ortholog, it has been shown to function as a nuclear protein with transcriptional repressor activity, potentially playing a regulatory role during spermatogenesis[1]. There is no strong evidence that TEX13B is a therapeutic target, nor are there validated disease relationships or recognized drugs that interact with it. It is best classified as a testis-specific, germ cell nuclear protein with a putative regulatory function in male germline development[1][2][5].

Other names
TSGA5TGC3Btestis expressed 13Btestis-expressed protein 13Btestis expressed sequence 13Btestis-expressed sequence 13B protein
02

Biological functions

Possible involvement in transcriptional repression during spermatogenesis
03

Disease associations

No well-established disease associationAmme complex association noted but not well defined

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