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Target intelligence / Profile preview
Testis-expressed protein 2 (TEX2)
- Target
- TEX2
- Molecular classification
- Other (transmembrane protein, non-receptor), not currently classified as a receptor, enzyme, ion channel, or transporter
01
Overview
Testis-expressed protein 2 (TEX2) is a transmembrane protein encoded by the TEX2 gene, highly expressed in testicular tissue. It is predicted to localize to the endoplasmic reticulum membrane and may facilitate contact between the ER and the medial-Golgi complex, potentially influencing lipid transport and response to ER stress or increased ceramide. There are no confirmed drug interactions or established functional roles in human disease, and it is not recognized as a therapeutic target at present.
- Other names
- Testis expressed 2KIAA1738TMEM96HT008Transmembrane protein 96testis-expressed sequence 2 protein
02
Mechanism of action
None (no drugs currently known to target TEX2)
03
Biological functions
May function in the formation of membrane contact sites between the endoplasmic reticulum and medial-Golgi complex, particularly during endoplasmic reticulum (ER) stress or when cellular ceramide levels increasePredicted to be involved in lipid binding and lipid transport; localized predominantly to the endoplasmic reticulum membrane
04
Disease associations
Other (no established direct disease associations or clinical relevance as a therapeutic target currently documented)
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