Target intelligence / Profile preview

Testis-expressed protein 53 (TEX53)

Target
TEX53
Molecular classification
Other (protein with no established molecular function or family assignments)
01

Overview

Testis-expressed protein 53 (TEX53) is a protein-coding gene that is primarily expressed in the testis and cataloged under various gene and protein databases (HGNC: 53655, NCBI Gene: 105376230, UniProt: A0A1B0GU33). There is minimal experimental evidence describing its molecular or biological function, and TEX53’s formal classification or role in any signaling, transcriptional, or receptor-related processes is lacking. The only disease association is a statistical linkage to spermatogenic failure 8, with no mechanistic clarity. No drug interactions, mechanisms of action, or biomarker applications have been reported, and the gene is not considered a therapeutic target.

Other names
TEX53Testis-expressed protein 53TEX53phTEX53UniProt: A0A1B0GU33NCBI Gene: 105376230
02

Biological functions

Other (no experimentally validated biological functions; gene associated with testis expression)
03

Disease associations

Spermatogenic failure 8 (biostatistical association; causative or mechanistic role unclear)

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