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Target intelligence / Profile preview
Testis-specific basic protein Y 2C (BPY2C)
- Target
- BPY2C
- Molecular classification
- Other
01
Overview
BPY2C is a testis-specific nuclear protein encoded by a Y-chromosomal gene. It influences sperm cell development via modulating gene expression and chromatin structure. Loss or deletion can contribute to male infertility. The gene/protein is not considered a therapeutic target.
- Other names
- BPY2ABPY2BBPY2VCY2VCY2AVCY2BVCY2CTestis-specific basic protein Y 2Basic charge, Y-linked 2Basic protein on Y chromosome 2Variable charge, Y-linked 2Variably charged protein Y 2
02
Biological functions
Male germ cell developmentSpermatogenesisUbiquitin ligase bindingChromatin/DNA regulation
03
Disease associations
Male infertilitySpermatogenic failureOligozoospermiaAzoospermia
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