Target intelligence / Profile preview

Testis-specific gene 13 protein (TSGA13)

Target
TSGA13
Molecular classification
Other
01

Overview

Testis-specific gene 13 protein (TSGA13) is a conserved protein-coding gene predominantly expressed in the testis, but with lower expression in tissues such as stomach, larynx, spleen, bladder, tonsil, liver, and thyroid. Its precise biological function remains unclear, though it may be involved in protein binding and possibly processes related to testis-specific gene expression. TSGA13 protein is significantly downregulated in most carcinoma tissues compared to normal tissues, except glioblastoma and lung cancer, suggesting a possible connection to malignancy. Disease associations include hereditary retinal dystrophy and colonic aganglionosis, but there are no known drug interactions or recognized use as a therapeutic, biomarker, or safety concern. The gene is conserved among species and has several orthologues. If you need additional details on sequence, structure, orthologs, or phenotype data, this gene is annotated across major genetics and protein databases.

Other names
TSGA13Testis-specific gene 13 proteintestis-specific A13TSG13
02

Biological functions

protein bindingPutative role in testis-specific gene expression or function
03

Disease associations

Hereditary retinal dystrophyColonic aganglionosisPutative association with malignancy/tumor biology

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