Testis specific protein Y-linked 6, pseudogene (TSPY6P)

Testis specific protein Y-linked 6, pseudogene (TSPY6P) is a non-coding, Y chromosome-linked pseudogene in humans. It belongs to the TSPY (testis specific protein, Y-encoded) gene family, which includes functional genes and multiple transcripts on the Y chromosome involved in male germ cell development and as cancer/testis antigens. However, TSPY6P itself is annotated as a pseudogene, meaning it does not encode a functional protein and has no demonstrated biological activity or clinical significance as a direct molecular target. The functional TSPY gene (not this pseudogene) has been implicated in testis development, male infertility, and some cancers, but TSPY6P does not share these properties. TSPY6P is a pseudogene, not a protein-coding gene, and therefore does not produce a functional protein or serve as a target for drugs or therapies. Its canonical gene symbols, aliases, and synonyms include "testis specific protein Y-linked 6, pseudogene," "TSPYP6," "CT78," and "DYS14". There is no evidence for its direct involvement in disease, drug response, or use as a biomarker. Distinct from the active TSPY gene family member, which is a cancer/testis antigen and proto-oncogene, TSPY6P has no known biological or therapeutic function. If a therapeutic target is required, TSPY6P is not suitable, as it is not an enzyme, receptor, transporter, nor does it encode a protein. The entry is accurate but should be distinguished from its functional homologs.

Other names

testis specific protein, Y-linked 6, pseudogeneTSPYP6TSPY6Ptestis specific protein, Y-linked pseudogene 6CT78DYS14tspyp6