Target intelligence / Profile preview

Testis-specific serine kinase substrate (TSKS)

Target
TSKS
Molecular classification
Other
01

Overview

Testis-specific serine kinase substrate (TSKS) is a protein expressed predominantly in the testis, likely involved in the processes of spermatogenesis and spermiogenesis[4]. TSKS serves as a substrate for testis-specific serine/threonine kinases such as TSSK1 and TSSK2[1], participating in protein phosphorylation events crucial for normal sperm development and function. Its role is implicated in testicular physiology and male fertility, but it is not classified as a receptor, enzyme, or a direct therapeutic target. If your focus is on the testis-specific serine kinases (TSSK1, TSSK2, etc.), those are considered druggable targets and have distinct information profiles as kinases involved in male fertility and spermatogenesis[1][8].

Other names
TSKS
02

Biological functions

SpermatogenesisSpermiogenesisTesticular physiology
03

Disease associations

Male infertility

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