Tetraspanin 12 pseudogene

Tetraspanin 12 pseudogene refers to a genomic region with sequence similarity to the Tetraspanin 12 (TSPAN12) gene, but due to mutations such as frameshifts or premature stop codons, it is not transcribed or translated into a functional protein. Pseudogenes are remnants of gene duplication or retrotransposition events and are considered non-functional. They are distinct from the active, protein-coding TSPAN12 gene (ENSG00000106025), which is a regulator of the Norrin/β-catenin signaling pathway essential for retinal vascular development; however, the pseudogene itself has no known function, therapeutic relevance, or disease association. The target is not a functional protein or therapeutic target, but rather a non-coding, non-protein-producing pseudogene. It should not be selected as a drug discovery or biomarker target. If your pipeline requires protein-coding, functional targets, map requests for this pseudogene to null or flag as incorrect selection. No evidence supports a role for "tetraspanin 12 pseudogene" as a receptor, enzyme, or disease target.

Other names

LOC100287840ENSG00000270631tetraspanin 12 pseudogene