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Tetratricopeptide repeat domain 34 pseudogene

Molecular classification
Pseudogene, Derived from a gene encoding a protein with a tetratricopeptide repeat domain
01

Overview

Tetratricopeptide repeat domain 34 pseudogene (LOC100421684, ENSG00000271632) is classified as a pseudogene, meaning it is a segment of DNA that resembles a gene but is nonfunctional in terms of protein-coding potential. It is not considered a therapeutic target, and there is no evidence it encodes a receptor, enzyme, transporter, or has a known biological activity. Some pseudogenes can produce noncoding RNAs that regulate the expression of related protein-coding genes through RNA interference and other mechanisms, and in rare cases are implicated in disease, but there is no evidence for such a function in this specific pseudogene[2][5].\nThe parent gene would have contained a tetratricopeptide repeat (TPR) structural motif, which is known for mediating protein-protein interactions in a wide range of scaffolding, cell cycle, and signaling proteins[1][4][6][7]. However, this pseudogene does not code for a functional TPR-domain protein[2].

Other names
LOC100421684ENSG00000271632TPR domain 34 pseudogene
02

Biological functions

No protein productDoes not have a canonical biological functionPseudogenes can potentially regulate gene expression via noncoding RNA mechanisms
03

Disease associations

Pseudogenes have been implicated in gene regulationMay play roles in disease, notably cancerNo evidence is available for this specific pseudogene

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