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The tetratricopeptide repeat domain 5 pseudogene (ENSG00000257128, LOC100129078) is a noncoding genomic sequence highly similar to the protein-coding gene TTC5, but it does not give rise to a functional protein. Pseudogenes are typically considered evolutionary relics and do not participate in coding cellular functions, serving no direct therapeutic or biological role. By contrast, the functional TTC5 gene encodes a transcription coactivator involved in regulation of mRNA degradation and neuronal development, but LOC100129078 itself is not functionally active and is not considered a target in medical or pharmacological research.
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