Target intelligence / Profile preview

Tetratricopeptide repeat protein 9A (TTC9)

Target
TTC9
Molecular classification
Other (TPR domain-containing protein)
01

Overview

Tetratricopeptide repeat protein 9A (TTC9) is a protein containing several tetratricopeptide repeat (TPR) motifs, which are known for mediating protein-protein interactions. TTC9 is hormonally regulated in breast cancer cells and may contribute to cancer cell invasion and metastasis. It is involved in molecular pathways related to mammary gland development and has been associated with invasive bladder transitional cell carcinoma. Functionally, TTC9 is considered a chaperone protein participating in protein folding[1][2][4].

Other names
Tetratricopeptide repeat domain 9KIAA0227TTC9ATPR repeat protein 9A
02

Biological functions

Protein-protein interactionprotein folding chaperonehormonally regulated gene (notably in breast cancer cells)potential role in cancer cell invasion and metastasis
03

Disease associations

Cancer (breast cancer, invasive bladder transitional cell carcinoma)

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