Target intelligence / Profile preview

Thiol-Disulfide Exchange

Molecular classification: Chemical Reaction, Post-translational Modification

Overview

Thiol-disulfide exchange is a chemical reaction in which a thiolate anion attacks and cleaves a disulfide bond, resulting in the formation of a new disulfide bond and the release of another thiolate. This process is central to protein folding, redox regulation, and cellular signaling.

Biological functions

Protein foldingRedox regulationSignal transduction

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