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Target intelligence / Profile preview
Thioredoxin (TRX)
- Target
- TRX
- Molecular classification
- Redox protein, Oxidoreductase
01
Overview
Thioredoxins are essential small proteins that maintain cellular redox balance, protect against oxidative damage, regulate key metabolic/signaling processes across all life forms—and have emerging clinical significance both diagnostically and therapeutically.
- Other names
- Trx-1Trx-2TXNTXN2
02
Mechanism of action
Dithiol-disulfide exchange
03
Biological functions
Redox regulationAntioxidant defenseEnzyme regenerationCell signalingApoptosis regulationDNA synthesisImmune modulation
04
Disease associations
CancerCardiovascular diseaseInflammatory diseases
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