Thoracodorsal nerve

The **thoracodorsal nerve** is a peripheral motor nerve that arises from the posterior cord of the brachial plexus, with fibers originating from cervical nerves C6–C8[1][2][3][5]. It is also known as the **middle subscapular nerve** or **long subscapular nerve**. Its primary function is to provide motor innervation to the latissimus dorsi muscle, which plays a crucial role in movements such as shoulder adduction, internal rotation, extension, and stabilization during activities like climbing or swimming[1][2][4][5]. The thoracodorsal nerve does not have sensory functions[6]. It can be injured during surgical procedures involving the axilla (e.g., mastectomy), leading to weakness in arm movement and impaired function of the latissimus dorsi. While it has clinical significance for surgeons—especially in reconstructive procedures—it is not considered a molecular therapeutic target such as a receptor, enzyme, transporter, or similar druggable entity[1][2][3]. **Note:** The thoracodorsal nerve is an anatomical structure (a peripheral motor nerve), not a molecular target like receptors or enzymes. Therefore, - It should not be classified as a therapeutic "target" in pharmacological terms. - There are no drugs that directly interact with this structure. - Mechanisms of action and biomarkers relevant for drug targeting do not apply. If you are seeking information on molecular targets involved in neuromuscular transmission or related pathways at this anatomical site (e.g., acetylcholine receptor at neuromuscular junction), please specify further.

Other names

middle subscapular nervelong subscapular nerve