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Target intelligence / Profile preview
Thrombospondin-1 Receptor (CD36)
- Target
- CD36
- Molecular classification
- Scavenger receptor, Transmembrane protein, Glycoprotein
01
Overview
CD36, also known as the thrombospondin-1 receptor, is a multifunctional integral membrane glycoprotein and member of the class B scavenger receptor family. It is widely expressed on various cell types and plays crucial roles in fatty acid metabolism, inflammation, angiogenesis, and immunity, making it a potential therapeutic target for various diseases.
- Other names
- Platelet glycoprotein 4Fatty acid translocase (FAT)Scavenger receptor class B member 3 (SCARB3)Glycoproteins GP88/GPIV/GPIIIBPAS IV
02
Mechanism of action
Unknown
03
Biological functions
Fatty acid uptake and metabolismScavenger receptor activityThrombospondin-1 receptor activityImmune regulationAngiogenesis regulation
04
Disease associations
AtherosclerosisCardiovascular diseaseDiabetesMetabolic syndromeObesityHypertensionCardiomyopathyAlzheimer's diseaseNeurodegenerationCancer
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