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Target intelligence / Profile preview
Thrombospondin type-1 domain-containing protein 8 (THSD8)
- Target
- THSD8
- Molecular classification
- Other (Extracellular matrix-associated protein/Thrombospondin domain-containing protein)
01
Overview
Thrombospondin type-1 domain-containing protein 8 (THSD8) is a protein encoded by the *THSD8* gene in humans. It is classified as a protein-coding gene located on chromosome 19p13.13. The protein contains thrombospondin type-1 domains, which are generally involved in extracellular matrix interactions and cell–cell communication, but the specific molecular function and biological processes associated with THSD8 are currently unknown. Predictive data suggest it may be localized to the external side of the plasma membrane and the sperm head plasma membrane. There are no known drugs, disease associations, or functional data indicating a therapeutic target role for THSD8.
- Other names
- Thrombospondin type-1 domain-containing protein 8THSD8THSD8 gene
02
Mechanism of action
Not defined/None known. As no drugs target THSD8, mechanisms are not established.
03
Biological functions
Unknown/Not fully characterized. The specific molecular and cellular functions of THSD8 remain undefined. It is predicted to be associated with the plasma membrane and may play a role in extracellular matrix interactions, as with other thrombospondin family proteins.Proteins with thrombospondin type-1 domains are broadly involved in cell–cell and cell–matrix interactions, but functional details for THSD8 specifically are lacking.
04
Disease associations
Other (No known direct disease association noted)
05
Safety considerations
None reported. No therapeutic or interventional use, so no documented safety profile
06
Interacting drugs
None known
07
Biomarkers
None known
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