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Target intelligence / Profile preview
Thyroid Follicular Cell (Thyrocyte)
- Target
- Thyrocyte
- Molecular classification
- Epithelial Cell, Endocrine Cell
01
Overview
Thyroid follicular cells, also known as thyrocytes or thyroid epithelial cells, are the principal cell type in the thyroid gland. They are responsible for the synthesis and secretion of thyroid hormones—primarily thyroxine (T4) and triiodothyronine (T3)—which play a critical role in regulating metabolism throughout the body.
- Other names
- Thyroid epithelial cell
02
Mechanism of action
N/A (Cells are not directly targeted by drugs, but their function is modulated)
03
Biological functions
Synthesis of thyroglobulinIodide uptake and transportThyroid hormone (T3/T4) synthesis and secretionRegulation of metabolism
04
Disease associations
HypothyroidismHyperthyroidismThyroid cancerGoiterThyroiditis
05
Safety considerations
Thyroid hormone overdose (hyperthyroidism)Thyroid hormone deficiency (hypothyroidism)Drug-induced thyroid dysfunctionRadiation exposure (radioactive iodine)Autoimmune thyroid disease
06
Interacting drugs
Levothyroxine
5 more in the full profile.
07
Biomarkers
Thyroglobulin (TG)Thyroid-stimulating hormone (TSH)Thyroxine (T4)Triiodothyronine (T3)Anti-thyroglobulin antibodiesAnti-thyroid peroxidase antibodies
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