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TIPARP antisense RNA 1 (TIPARP-AS1)

Target
TIPARP-AS1
Molecular classification
Long non-coding RNA (lncRNA)
01

Overview

TIPARP antisense RNA 1 (TIPARP-AS1), also known as LINC00886, is a long non-coding RNA (lncRNA) gene located at 3q25.31 on chromosome 3[2][3][4]. It is classified as an lncRNA and does not code for a protein. TIPARP-AS1 is transcribed antisense to the TIPARP (TCDD Inducible Poly(ADP-Ribose) Polymerase) gene. Its specific biological function has not been characterized in detail, and it is not recognized as a protein-coding target, receptor, enzyme, transporter, or established therapeutic target[2][3][4]. Some databases list it among genes associated with disease, but there are currently no approved drugs or specific therapeutic mechanisms of action targeting TIPARP-AS1, nor is it used as a biomarker in clinical practice. Clarifications based on guidelines: - TIPARP-AS1 / LINC00886 is not a therapeutic target (not a receptor, enzyme, transporter, etc.) and is best classified as a long non-coding RNA[3][4]. - No known interacting drugs, mechanisms of action, or prominent disease roles are established to date[3][4]. - No apparent incorrectness in target naming, but not a classic druggable target.

Other names
LINC00886Long intergenic non-protein coding RNA 886
02

Biological functions

Unknownregulatory non-coding RNA
03

Disease associations

Other (There are reports of disease association but no well-defined, specific pathogenic role)

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