Tissue regeneration scaffold

Tissue regeneration scaffolds are engineered three-dimensional biomaterials—either natural, synthetic, or hybrid—that are designed to mimic the extracellular matrix (ECM) of native tissue. They provide physical and biochemical cues needed for cell attachment, proliferation, migration, differentiation, and tissue maturation, serving as a temporary structure for new tissue growth in regenerative medicine applications. Essential scaffold properties include high porosity, interconnected pore structure, biocompatibility, appropriate mechanical strength, controlled degradation rates, and, where relevant, the ability to deliver cells and biologically active molecules. Scaffolds can be used alone, seeded with cells, or impregnated with growth factors to promote the repair or regeneration of damaged tissues and organs.

Other names

Tissue engineering scaffoldregenerative scaffoldtissue scaffoldtissue-engineered scaffoldbiomaterial scaffold

Function as a 3D substrate mimicking extracellular matrix, enabling and supporting cellular organization and eventual replacement by new tissue. Controlled delivery of regulatory molecules (e.g., growth factors) incorporated in scaffold materials.